WebDec 7, 2015 · Rationale Respiratory syncytial virus (RSV) infection in preterm and newborn infants can result in severe bronchiolitis and hospitalization. The lamb lung has several key features conducive to modeling RSV infection in human infants, including susceptibility to human strains of RSV such as the A2, Long, and Memphis Strain 37 (M37). In this study, … WebRSV Memphis-37 was isolated from a child with bronchiolitis, characterized, and manufactured for use as a challenge virus in the adult experimental infection model. It supports safe, reproducible, quantifiable, and transient RSV infection and respiratory disease manifestations in adult volunteers. The virus has been
RSV: New drug shows promise against respiratory virus, study …
WebNov 21, 2014 · RSV Memphis-37 was isolated from a child with bronchiolitis, characterized, and manufactured for use as a challenge virus in the adult experimental infection model. It supports safe, reproducible, quantifiable, and transient RSV infection and respiratory disease manifestations in adult volunteers. WebHuman respiratory syncytial virus Memphis 37 grown in HEp-2 cells causes more severe disease in lambs than virus grown in vero cells. Viruses. 5 (11):2881-2897. DOI: 10.3390/v5112881. Interpretive Summary: Respiratory syncytial virus (RSV) is a virus that is present worldwide, causing a range of respiratory disease. steelcase credenza cabinet with drawers
Respiratory syncytial virus human experimental infection model ... - PubMed
WebWe hypothesized that the Memphis 37 strain of RSV would infect perinatal lambs and produce clinical disease similar to that in human infants. Perinatal (3- to 5-day-old) lambs were inoculated intranasally with 2 mL/nostril of 1×10 5 focus-forming units (FFU)/mL (n=2) or 2.1×10 8 FFU/mL (n=3) of RSV Memphis 37. Clinical signs, gross and ... WebApr 1, 2014 · The Memphis 37 clinical strain of human RSV has been used to produce mild to moderate upper respiratory disease in healthy adult volunteers. We hypothesized that … WebJun 24, 2024 · Dr. Hysmith is talking about a sharp rise in recent weeks of respiratory syncytial virus - or RSV. "Touching things, coughing, sneezing, those kind of things, is how RSV is spread," Dr. Hysmith... steelcase conference table round